Oral Hairy Leukoplakia and Oral Candidiasis
In Patient with HIV/AIDS

Dorisna Prijaryanti 1, Toni Masruri 2, Desiana Radithia 3 4, Bagus Soebadi3 4

Oral Medicine Residency Program,Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

Oral Medicine Residency Program, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia

Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya Indonesia

Oral Medicine Clinic, Universitas Airlangga Dental Hospital, Surabaya, Indonesia


Objective: Oral candidiasis (OC) and Oral hairy leukoplakia (OHL) are infections that are often found in patient with Human Immunodeficiency Virus (HIV) or Acquired Immune Deficiency Syndrome (AIDS). Symptoms of Oral Candidiasis include poor in taste sensation, discomfort when eating spicy food, and burning mouth sensations, while oral hairy leukoplakia is usually painless so patients often do not recognise it. This paper provides a case report of 17-year-old male complaining of discomfort all over the surface of the tongue and a reduced taste sensation for over a year. As well as continuous diarrhea the patient had lost 8kg in one year.


Methods: Diagnosis of OC based on history taking, clinical feature and microscopically while diagnosis for OHL based on clinical characteristic sign. HIV diagnosis by HIV Rapid Test (oncoprobe, vikia), Elisa and CD4. Treatment of OC with 200mg ketoconazole twice daily, Chlorhexidine gluconate 0,2% four times daily and 2ml of Nystatin suspension four times daily and OHL treatment requires 200mg of Acyclovir five times a day, and ARV to treatment of HIV.


Result: The Candida has reduced after 3 weeks treatment, before receiving ARV therapy. After receiving ARV therapy for over 1 month OC and OHL healed.


Conclusion: The treatment of Oral candidiasis for HIV/AIDS requires systemic antifungals and long-term antiretroviral drugs, therefore good cooperation between the operator and patient is required, as well as patient compliance in taking medication and following regular control.


Keyword: Oral candidiasis, Oral hairy leukoplakia, HIV/AIDS